Compared with human bone marrow-derived mesenchymal stem cells (hBMSCs), human umbilical cord-derived mesenchymal stromal cells (hUCMSCs) have the advantages of abundant supply, painless collection, no donor site morbidity, and faster and longer self-renewal in vitro. In this 6-week study, a chondrogenic (forming cartilage from condensed mesenchyme tissue) comparison was conducted of hBMSCs and hUCMSCs in a three-dimensional (3D) scaffold for the first time.

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