Mesenchymal stem cells (MSCs) from Wharton’s jelly present high plasticity and low immunogenicity, making them a desirable form of cell therapy for an injured nervous system. Their isolation, expansion, and characterization have been performed from cryopreserved umbilical cord tissue. The MSCs from Wharton’s jelly delivered through tested biomaterials should be regarded a potentially valuable tool to improve clinical outcome especially after trauma to sensory nerves. In addition, these cells represent a noncontroversial source of primitive mesenchymal progenitor cells, which can be harvested after a healthy birth, cryogenically stored, thawed, and expanded for therapeutic uses.

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